Promethazine Signals and signs of overdosage with promethazine range between gentle despair from the central anxious procedure and cardiovascular procedure to profound hypotension, respiratory depression, unconsciousness and unexpected death.
Normally, dose variety for an elderly affected individual must be careful, generally setting up on the low finish in the dosing range, reflecting the greater frequency of lessened hepatic, renal or cardiac operate, and of concomitant ailment or other drug therapy.
To lessen your possibility, your medical doctor ought to have you take the smallest dose that actually works, and get it to the shortest achievable time. See also How to Use part for more information about dependancy.
Consume a good amount of fluids if you are utilizing this medication Until normally directed by your health practitioner. The fluid can help loosen the mucus in the lungs.
g., Individuals with evidence of greater intracranial tension or Mind tumors), Promethazine HCl and Codeine Phosphate Oral Answer could cut down respiratory push, as well as resultant CO2 retention can additional increase intracranial pressure. Furthermore, opioids develop adverse reactions that will obscure the medical system of patients with head accidents.
To lower the potential risk of dizziness and lightheadedness, stand up slowly and gradually when mounting from a sitting down or lying place.
DailyMed will supply notification of updates and additions to Drug Label details now revealed on This great site by means of its RSS feed.
When the reaction to an opioid antagonist is suboptimal or only transient in mother nature, administer added antagonist as directed via the product or service’s prescribing info. The respiratory depressant outcomes of promethazine aren't reversed by opioid antagonists, for instance naloxone.
Promethazine could lower seizure threshold. It ought to be applied with warning in folks with seizure Issues or in people who will be working with concomitant remedies, which include narcotics or nearby anesthetics, which may also have an impact on seizure threshold.
The estimated track record chance of main birth defects and miscarriage for the indicated population is unfamiliar. All pregnancies Use a history possibility of delivery defect, loss, or other adverse outcomes.
Get this medication by mouth with or without the need of food stuff as directed by your medical professional, typically each individual 4 to 6 hours as essential. This medication is often taken with food stuff if belly upset occurs. Consume lots of fluids when you use this medication Except if otherwise directed by your health practitioner.
Even so, this outcome is just not constant and may be offset by an increased price of cervical dilation, which tends to shorten labor. Watch neonates subjected to opioids for the duration of labor for indications of extra sedation and respiratory melancholy.
When utilized for an extended time, this medication might not operate at the same time and may demand diverse dosing. Talk with your medical doctor if this medication stops Performing Promethazine codeine syrup perfectly.
If this SPL incorporates inactivated NDCs detailed via the FDA initiated compliance motion, They are going to be specified therefore.